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Indexed and Abstracted in : SCOPUS, Scimago Journal Ranking, Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Index Copernicus, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS. ISSN : 0975-3575 Frequency : Rapid at a time publication (6 issues/year) More than 50,000 readers in nearly every country in the world each month Pharmacognosy Journal (Phcog J.) covers different topics in natural product drug discovery, and also publishes manuscripts that describe pharmacognostic investigations, evaluation reports, methods, techniques and applications of all forms of medicinal plant researchĭistinctions: The most widely read, cited, and known Pharmacognosy journal and website is well browsed with all the articles published.
Conclusion: SSHT has antibacterial activity against Streptococcus pneumoniae, and SR and its major constituent baicalin contribute to the antibacterial activity of SSHT against Streptococcus pneumoniae. In this fraction, we found baicalin as the major compounds, and baicalin exhibited antibacterial activity against Streptococcus pneumoniae in concentration-dependent manner. Among them, only 80% EtOH soluble fraction was exhibited antibacterial activity. SR extract was partitioned into AcOEt, BuOH, and water layer, and water layer was further separated into 80% EtOH soluble and insoluble fraction.
Results: SSHT extract and each water extract of Ophiopogon Tuber, SR, Gardenia Fruit, Anemarrhena Rhizome, Lilium Bulb, Magnolia Flower, and Cimicifuga Rhizome showed significant antibacterial activity against Streptococcus pneumoniae, and SR extract exhibited the largest inhibitory zone. The diameter of inhibitory zone was measured after 20-24 h incubation. Materials and Methods: Sterile paper disks impregnated with SSHT extract or each extract of its component were placed on sheep blood agar plates inoculated with Streptococcus pneumoniae (ATCC 49619).
We evaluated anti-bacterial activity of SSHT extract on Streptococcus pneumoniae, the major cause of bacterial sinusitis. Objective: Shin'iseihaito (Xin yi qing fei tang in Chinese, SSHT), a formula in traditional Japanese Kampo medicine and Chinese medicine comprising nine crude drugs, Gypsum, Ophiopogon Tuber, Scutellaria Root (SR, root of Scutellaria baicalensis), Gardenia Fruit, Anemarrhena Rhizome, Lilium Bulb, Magnolia Flower, Loquat Leaf, and Cimicifuga Rhizome, is commonly used to treat sinusitis associated with purulent nasal discharge and reddish nasal mucosa.
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